Gloucester for me. No signs whatsoever of them weakening, their signings this summer suggesting they will become a serious force on the european stage this year. They lose a few internationals, but had the best record in the Premiership on international weekends last year and that will be an important factor as always. Dean Ryan is building something special here as they add experience to the good young side of last year and there is enough depth in the squad that a second XV would go well. A bit more firepower in the backs wont go amiss and the additions to the back-row are just what was needed. Worth a look in the Heineken too.
Leicester should push them all the way but without Shane Jennings, and with no replacement currently, I don't see them hitting quite the same highs. These two are clear of the rest in squad depth and that should tell. Their first XVs are handy too. Good chance of the same final at the end of the year, but maybe a different result?
Sale are my outside bet as an injury-free run would make them a real danger. Some of the best players around fill their starting XV and Luke McCallister could really have an impact, adding his boot, creativity and power to Hodgson's guile. Jason Robinson is a loss, but more important is getting players like White and particularly Hodgson available for the year. Keep the big names fit and I can see them finishing top 3 at least.
As for the rest I don't see enough depth in the squads. Saracens are the obvious contenders for the final play-off spot, but a lot depends on how many injuries each team picks up. As we move outside the top 2 injuries to key players will have a bigger impact so it could be down in part to who gets lucky.
For bottom of the table Leeds are obvious favourites and almost certainly need another team to have either an injury nightmare or simply play well below themselves for Leeds to stay up. Not that it's impossible for them to stay up, but it certainly seems more clear cut than last year. Wouldn't take too many injuries for Newcastle to suffer and Bath promise much but always look like they are on the edge of imploding.