Toulouse and France lock Romain Millo-Chluski is in doubt for the Six Nations after tearing a calf muscle in Paris on Saturday.
Millo-Chluski left the pitch in the 77th minute of Toulouse's 31-3 loss to Stade Français on Saturday.
Toulouse coach Guy Novès said on Monday that he doesn't think the player will have recovered in time for the tournament.
Better news for the club and country is the confirmation that fly-half David Skrela will be fit to play in the Heineken Cup this weekend after pulling out of the clash with Stade Français at the last minute with a tight hamstring.
France open their title defence against Scotland on February 5 at the Stade de France.
France coach Marc Lièvremont will announce his 30-man squad for the Six Nations next week.
