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<blockquote data-quote="Which Tyler" data-source="post: 1030716" data-attributes="member: 73592"><p>First mentioned 4 years ago: <a href="https://www.therugbyforum.com/threads/george-norths-concussion.38580/#post-870862" target="_blank">https://www.therugbyforum.com/threads/george-norths-concussion.38580/#post-870862</a></p><p>Brilliant that it's such a high specificity; if it's equally sensitive; then that'll be a real game-changer for management; though DNA testing (and time to create the biomarkers) is unlikely to ever reach pitch-side.</p><p></p><p>I'll be very interested to see the actual research (As far as I can tell, it's not been published yet)</p><p></p><p>ETA: Found it; just not listed on Pubmed yet: <a href="https://bjsm.bmj.com/content/early/2021/02/09/bjsports-2020-103274" target="_blank">https://bjsm.bmj.com/content/early/2021/02/09/bjsports-2020-103274</a></p><p></p><p>ETA: It's RNA testing, not DNA; which I think makes things comparatively easier / cheaper.</p><p>Gives good results in the post-game (undefined time post-injury event) and 36-48 hours post-game; so potentially (very) useful at the amateur level for collecting saliva before leaving the club.</p><p>Short-term (after more research and validation), I don't see this replacing current pitchside HIAs; or being particularly useful for elite sport. However, if this can be made validated with larger trial size, and get the costs down; then this will make a HUGE difference at amateur level.</p><p>Longer-term: It would be great if we can get some more accurate time-frames on sample collection, and even a pre-match base-line for each individual; combine that with much quicker sample testing, and it MIGHT get down to being useable pitch-side; as another part of the HIA</p></blockquote><p></p>
[QUOTE="Which Tyler, post: 1030716, member: 73592"] First mentioned 4 years ago: [URL]https://www.therugbyforum.com/threads/george-norths-concussion.38580/#post-870862[/URL] Brilliant that it's such a high specificity; if it's equally sensitive; then that'll be a real game-changer for management; though DNA testing (and time to create the biomarkers) is unlikely to ever reach pitch-side. I'll be very interested to see the actual research (As far as I can tell, it's not been published yet) ETA: Found it; just not listed on Pubmed yet: [URL]https://bjsm.bmj.com/content/early/2021/02/09/bjsports-2020-103274[/URL] ETA: It's RNA testing, not DNA; which I think makes things comparatively easier / cheaper. Gives good results in the post-game (undefined time post-injury event) and 36-48 hours post-game; so potentially (very) useful at the amateur level for collecting saliva before leaving the club. Short-term (after more research and validation), I don't see this replacing current pitchside HIAs; or being particularly useful for elite sport. However, if this can be made validated with larger trial size, and get the costs down; then this will make a HUGE difference at amateur level. Longer-term: It would be great if we can get some more accurate time-frames on sample collection, and even a pre-match base-line for each individual; combine that with much quicker sample testing, and it MIGHT get down to being useable pitch-side; as another part of the HIA [/QUOTE]
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