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Venue: Vicarage Road Date: Sunday, 27 September Kick-off: 1500
Saracens captain Steve Borthwick has been passed fit for the visit of Gloucester and he is joined in the second row by Mouritz Botha.
Wikus van Heerden returns to the back row and Fabio Ongaro starts at hooker.
Gloucester's summer signing Paul Doran-Jones makes his full debut, replacing Greg Sommerville at tight head.
Adam Eustace takes over from the banned Gareth Delve and James Simpson-Daniel, Rory Lawson, Olivier Azam, Peter Buxton and Alasdair Strokosch all start.
There were concerns about Borthwick after he suffered a serious-looking injury against Harlequins last weekend.
Scans revealed it to be a sprained rib cartilage but he was able to return to action earlier than expected.
Saracens: Goode, Cato, Ratuvou, Barritt, Wyles, Jackson, de Kock, Gill, Ongaro, Nieto, Borthwick (capt), Botha, van Heerden, Saull, Joubert.
Replacements: Brits, Aguero, Skuse, Vyvyan, Owen, Marshall, Hougaard, Haughton.
Gloucester: Voyce; Simpson-Daniel, Tindall (capt), Fuimaono-Sapolu, Vainikolo; Robinson, Lawson; Dickinson, Azam, Doran-Jones; Buxton, Brown; Strokosch, Qera, Eustace.
Replacements: Lawson, Knight, Capdevielle, Satala, Hazell, Lewis, Burns, Sharples.
BBC Sport
Venue: Vicarage Road Date: Sunday, 27 September Kick-off: 1500
Saracens captain Steve Borthwick has been passed fit for the visit of Gloucester and he is joined in the second row by Mouritz Botha.
Wikus van Heerden returns to the back row and Fabio Ongaro starts at hooker.
Gloucester's summer signing Paul Doran-Jones makes his full debut, replacing Greg Sommerville at tight head.
Adam Eustace takes over from the banned Gareth Delve and James Simpson-Daniel, Rory Lawson, Olivier Azam, Peter Buxton and Alasdair Strokosch all start.
There were concerns about Borthwick after he suffered a serious-looking injury against Harlequins last weekend.
Scans revealed it to be a sprained rib cartilage but he was able to return to action earlier than expected.
Saracens: Goode, Cato, Ratuvou, Barritt, Wyles, Jackson, de Kock, Gill, Ongaro, Nieto, Borthwick (capt), Botha, van Heerden, Saull, Joubert.
Replacements: Brits, Aguero, Skuse, Vyvyan, Owen, Marshall, Hougaard, Haughton.
Gloucester: Voyce; Simpson-Daniel, Tindall (capt), Fuimaono-Sapolu, Vainikolo; Robinson, Lawson; Dickinson, Azam, Doran-Jones; Buxton, Brown; Strokosch, Qera, Eustace.
Replacements: Lawson, Knight, Capdevielle, Satala, Hazell, Lewis, Burns, Sharples.
BBC Sport